At the Granot Lab, we are driven by a central question: how do immune cells, particularly neutrophils, control the balance between health and disease? Neutrophils are the immune system’s rapid-response force, capable of both protecting and damaging tissues. We investigate their molecular programs, signaling pathways and interactions with other cells using advanced techniques including live-cell imaging, transcriptomics and neutrophil-specific drug delivery platforms.

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Our research spans diverse contexts - from inflammatory diseases such as ulcerative colitis to tissue regeneration and the tumor microenvironment. Positioned at the intersection of fundamental immunology and translational medicine, we aim to uncover novel mechanisms of immune regulation and translate these insights into potential treatments. By integrating our discoveries with cutting-edge nanotechnology, we aim to design precise, cell-targeted therapies that reprogram immune function while avoiding systemic side effects.

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Through a multidisciplinary approach, international collaborations, and a commitment to mentoring the next generation of scientists, the Granot Lab is advancing the frontier of immune cell biology and its therapeutic potential.